What Are Clinical Trials?

The purpose of clinical trials is to find out whether a medication is safe to use and effective against various diseases or medical conditions.

How Are Clinical Studies of Mental Disorders Designed?

Clinical researchers call the standard scientific approach for trying out treatments a double-blind, randomized, controlled clinical trial. Understanding this term, and knowing how and why this approach is used, should help you to decide whether to become a research volunteer.

Why Do Patients Participate in Research on Mental Disorders?

Although remarkable progress has been made in defining and treating mental illnesses, some treatments are not effective for all persons or may have significant side effects. Thus, most people who agree to take part in studies of mental illness hope the research will produce knowledge about the disease itself — for example, the role of genetics in illness — or about treatments that will benefit them directly.

Will You Have Access to Those Drugs That Work After a Trial Is Complete?

Often, the company developing a new drug may try to see that you can continue to get it, even before the FDA has approved it for sale. You may be able to do this under what is termed a compassionate plea basis. This means that because the new drug has been so helpful, the manufacturer can give it to a physician, who may then prescribe it for you.

Checklist of Questions

So, you're considering taking part in a clinical trial...This can be a very satisfying experience, allowing you to help yourself now and to help others in the future. But what questions should you ask to help you make sure you really want to take part, and, if you do decide to go ahead, what should you expect along the way?

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